Dissolving dermal filler with Hyaluronidase

Dissolving dermal filler
Dissolving dermal filler

Hyaluronidase is naturally present in our bodies. It enhances the absorption of injected fluids from our bloodstream. Typically Hyaluronidase is a substance that is used to reduce the risk of tissue damage. It is responsible for breaking down the hyaluronic acid to increase drug absorption.

Hyaluronidase is known to be the spreading factor that breaks down the bonds between hyaluronic acid and promotes the natural cellular process. The reaction of hyaluronidase is depended on the type of hyaluronic acid used. Hyaluronidase must be able to interact with the binding properties of hyaluronic acid.

If you are worried about the use of hyaluronidase injection, it is important for you to have sufficient knowledge about the injection. This article would help you understand the link between hyaluronidase and dermal fillers. You’d also get to learn about the properties of hyaluronidase injection and what dosage is appropriate to use.

Read on to have an insight into hyaluronidase and why it is so popularly used in the aesthetic industry.

Hyaluronidase and dermal fillers 

Hyaluronidase is a popular drug that has become essential when you are opting to get dermal filler treatment done. If there are any unsatisfactory results, the hyaluronidase injections dissolve the hyaluronic acid and deactivate its result.

Hyaluronidase is an enzyme that softens the dermal filler immediately. It has a half-life of two minutes. Within 24 to 48 hours, it eliminates the effect of the dermal filler on your skin. It works well to dissolve hyaluronic acid.

Moreover, it is also used to soften other types of dermal fillers. Here is an important part to keep in mind that all dermal fillers are different and hyaluronidase has a different effect on them. If the filler has settled well into the tissue, you might require a few sessions to get rid of the filler.

With hyaluronidase injection, the areas with wide filler spread will dissolve in sections. You’d have to undergo multiple sessions to get rid of the filler. In addition, hyaluronidase also breaks down the filler that is old and has been built up by taking multiple sessions. If there is scar tissue that covers the filler, the hyaluronidase dissolves the scar and enhances the longevity of the filler.

There is no standard dose of hyaluronidase injection to get rid of the unwanted filler. Your dermatologist uses small doses of this substance to remove the filler. Sometimes, they might remove the filler that you want on your face.

The use of hyaluronidase for cosmetic treatments 

Hyaluronidase is popularly used in the aesthetic industry for cosmetic treatments. Voluma, Juvederm, Restylane are common brands that are used by skin specialists or dermatologists to soften the filler. Hyaluronidase is extremely safe to use on your skin.  

It is used for the treatment of scars, skin grafting, and dealing with the complications of dermal fillers.

The more people are opting for dermal fillers to prevent wrinkles and fine lines on their skin, the more the use of hyaluronidase is increasing. One of the common uses of hyaluronidase in the cosmetic industry is its ability to reverse filler.

You don’t have to be unhappy about the unwanted filler on your face. The inappropriate placement of the filler on your face can be removed by injecting hyaluronidase in small amounts. This substance is used to contour the age-related changes of your face.


Make sure that you choose a professional and experienced doctor to use this substance. It could affect the production of natural hyaluronic acid in your body if not used correctly. Moreover, ensure that you go through an allergic reaction test. A patch test would let you know whether it is safe to use on your skin. If there is any form of swelling or redness, you should avoid using it.

Your doctor needs to be fully aware of the use of hyaluronidase substances and how to crosslink it with hyaluronic acid.



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